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| Nomenclature |
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Symbol:
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Tg(Igh-V-CD40lg)#Tsub
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Name:
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transgene insertion, Takeshi Tsubata
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MGI ID: |
MGI:4461029 |
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Synonyms: |
CD154TG, CD40L/B |
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Transgene:
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Tg(Igh-V-CD40lg)#Tsub
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C57BL/6
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: An Igh-V promoter, the Igh intron enhancer, and the Igk 3' enhancer were used to drive expression of the CD40lg cDNA. (J:128824)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Notes |
Phenotypic Similarity to Human Syndrome: IBD- Inflammatory Bowel Disease
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| References |
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Original: |
J:128824
Higuchi T et al.,
"Cutting Edge: Ectopic expression of CD40 ligand on B cells induces lupus-like autoimmune disease."
J Immunol 2002 Jan 1;168(1):9-12
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All: |
6 reference(s)
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Analysis Tools
