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| Nomenclature |
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Symbol:
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Gt(ROSA)26Sortm6(Gli1)Amc
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Name:
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gene trap ROSA 26, Philippe Soriano;
targeted mutation 6, Andrew P McMahon
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MGI ID: |
MGI:4460761 |
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Synonyms: |
R26-Gli1, RosaGli1-FLAG |
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Gene:
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Gt(ROSA)26Sor
Location:
Chr6:113067428-113077333 bp, - strand
Genetic Position: Chr6,
52.73 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:121411
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Parent Cell Line:
| Other (see notes) (ES Cell) |
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Strain of Origin:
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129 and C57BL/6 and CBA and Swiss Webster
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutation: | |
Insertion |
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Mutation details: A full-length Gli1 with a C-terminal 3X FLAG tag as well as an IRES2-Venus were inserted into the locus upstream of a floxed neo selection cassette. Upon cre expression, the cassette is removed and FLAG tagged Gli1-Venus is expressed. (J:121411)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
ES cell line = YFP3.1, a male ES cell line carrying Tg(CAG-cre/Esr1*)5Amc and is compound heterozgous at Gt(ROSA)26Sor: Gt(ROSA)26Sortm1Sor and Gt(ROSA)26Sortm1(EYFP)Cos.
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| References |
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Original: |
J:121411
Vokes SA et al.,
"Genomic characterization of Gli-activator targets in sonic hedgehog-mediated neural patterning."
Development 2007 May;134(10):1977-89
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All: |
3 reference(s)
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Analysis Tools
