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| Nomenclature |
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Symbol:
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Slitrk5tm2Vlcg
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Name:
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SLIT and NTRK-like family, member 5;
targeted mutation 2, Velocigene
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MGI ID: |
MGI:4459459 |
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Gene:
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Slitrk5
Location:
Chr14:111675115-111683134 bp, + strand
Genetic Position: Chr14,
57.86 cM, cytoband E3
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:160616
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Velocigene technology was used to replace the coding region with TM-lacZ and selection cassette, inserted at amino acid 47 after the initiator methionine, amino acid 7 after the signal sequence cleavage site. LacZ expression was detected in mice. (J:160616)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Slitrk5 Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:160616
Shmelkov SV et al.,
"Slitrk5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive-like behaviors in mice."
Nat Med 2010 May;16(5):598-602, 1p following 602
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All: |
1 reference(s)
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Analysis Tools
