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| Nomenclature |
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Symbol:
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Cdh2312J
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Name:
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cadherin 23 (otocadherin);
12 Jackson
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MGI ID: |
MGI:4453135 |
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Synonyms: |
Cdh23erl, Cdh23nmf308, erl, erlong, NMF308 |
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Gene:
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Cdh23
Location:
Chr10:60302748-60696490 bp, - strand
Genetic Position: Chr10,
30.11 cM
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Mutation
origin |
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Strain of Origin:
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C57BL/6J
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Single point mutation |
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Mutation details: This mutation comprises a T to C transition at nucleotide position 208 that results in replacement of serine by proline at amino acid position 70 (S70P). (J:174758)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Cdh23 Mutation:
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58 strains or lines available |
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| References |
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Original: |
J:174758
Han F et al.,
"A new mouse mutant of the Cdh23 gene with early-onset hearing loss facilitates evaluation of otoprotection drugs."
Pharmacogenomics J 2010 Jul 20;():
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All: |
3 reference(s)
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Analysis Tools
