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| Nomenclature |
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Symbol:
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Cd4tm3.2Litt
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Name:
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CD4 antigen;
targeted mutation 3.2, Dan R Littman
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MGI ID: |
MGI:4452053 |
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Synonyms: |
E4Pdelta |
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Gene:
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Cd4
Location:
Chr6:124864692-124888221 bp, - strand
Genetic Position: Chr6,
59.17 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:158962
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (other) |
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Mutations: | |
Insertion, Intragenic deletion |
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Cre mediated recombination removes the proximal enhancer upstream of exon 1. (J:158962)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Cd4 Mutation:
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42 strains or lines available |
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| References |
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Original: |
J:158962
Chong MM et al.,
"Epigenetic propagation of CD4 expression is established by the Cd4 proximal enhancer in helper T cells."
Genes Dev 2010 Apr 1;24(7):659-69
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All: |
1 reference(s)
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Analysis Tools
