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| Nomenclature |
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Symbol:
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Ptentm1.2Mwst
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Name:
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phosphatase and tensin homolog;
targeted mutation 1.2, Michael Weinstein
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MGI ID: |
MGI:4442327 |
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Synonyms: |
Ptendelta4-5 |
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Gene:
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Pten
Location:
Chr19:32757497-32826160 bp, + strand
Genetic Position: Chr19,
28.14 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:158751
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A loxP site was inserted upstream of exon 4 and a floxed neo allele was inserted downstream of exon 5. Cre mediated recombination removed the neo cassette and exons 4 and 5. (J:158751)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Pten Mutation:
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36 strains or lines available |
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| References |
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Original: |
J:158751
Wang H et al.,
"Allele-specific tumor spectrum in Pten knockin mice."
Proc Natl Acad Sci U S A 2010 Mar 16;107(11):5142-7
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All: |
1 reference(s)
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Analysis Tools
