|
|
| Nomenclature |
|
Symbol:
|
Ptprcltng
|
|
Name:
|
protein tyrosine phosphatase, receptor type, C;
lightning
|
|
MGI ID: |
MGI:4441612 |
|
Synonyms: |
PtprcL |
|
Gene:
|
Ptprc
Location:
Chr1:138062861-138175305 bp, - strand
Genetic Position: Chr1,
60.73 cM
|
|
Mutation
origin |
|
Strain of Origin:
|
C57BL/6
|
|
Mutation
description |
|
Allele
Type: | |
Chemically induced (ENU) |
|
Mutation: | |
Nucleotide substitutions |
| |
|
Mutation details: ENU induced at T to C transition that results in the amino acid substitution of serine for phenylalanine at position 503 (F503S). Flow cytometry confirmed that protein half-life is reduced. (J:158876)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:158876
Zikherman J et al.,
"CD45-Csk phosphatase-kinase titration uncouples basal and inducible T cell receptor signaling during thymic development."
Immunity 2010 Mar 26;32(3):342-54
|
|
All: |
2 reference(s)
|
|
Analysis Tools
