|
|
| Nomenclature |
|
Symbol:
|
Fli1tm1Matr
|
|
Name:
|
Friend leukemia integration 1;
targeted mutation 1, Maria Trojanowska
|
|
MGI ID: |
MGI:4441373 |
|
Synonyms: |
Fli1flox |
|
Gene:
|
Fli1
Location:
Chr9:32422208-32541368 bp, - strand
Genetic Position: Chr9,
17.74 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:158658
|
|
Parent Cell Line:
| Not Specified (ES Cell) |
|
Strain of Origin:
|
129P2/OlaHsd
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (Floxed/Frt) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: A loxP site was inserted upstream of exon 3 and an frt flanked neo cassette with a 3' loxP site was inserted downstream of exon 4. Flp mediated recombination removed the neo cassette leaving exons 3 and 4 floxed. (J:158658)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Fli1 Mutation:
|
2 strains or lines available |
|
| References |
|
Original: |
J:158658
Asano Y et al.,
"Endothelial Fli1 deficiency impairs vascular homeostasis: a role in scleroderma vasculopathy."
Am J Pathol 2010 Apr;176(4):1983-98
|
|
All: |
1 reference(s)
|
|
Analysis Tools
