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| Nomenclature |
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Symbol:
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Tg(Eno2-MFN2*R94Q)L51Ugfm
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Name:
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transgene insertion L51, University of Geneva Faculty of Medicine
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MGI ID: |
MGI:4440895 |
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Synonyms: |
hMFN2R94QL51, MitoCharc1, mitofusin2R94Q |
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Transgene:
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Tg(Eno2-MFN2*R94Q)L51Ugfm
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x DBA/2)F1
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The MitoCharc1 transgene was designed with the human Mitofusin 2 (MNF2) gene driven by a rat enolase (Eno2) promoter. Amino acid 94 of MNF2 was mutated from an Arginine (R) to a Glutamine (Q) to mimic the most commonly mutated residue in Charcot-Marie-Tooth disease type 2A (CMT2A). Line L51 was established. (J:158936)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:158936
University of Geneva Faculty of Medicine,
"DDS for transgene from Ugfm"
MGI Direct Data Submission 2010;():
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All: |
2 reference(s)
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Analysis Tools
