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| Nomenclature |
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Symbol:
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Tg(CAG-VCP*A232E)93Jpat
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Name:
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transgene insertion 93, J Paul Taylor
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MGI ID: |
MGI:4440440 |
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Synonyms: |
VCP-A232E |
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Transgene:
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Tg(CAG-VCP*A232E)93Jpat
Location:
unknown
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The CAG promoter was used to drive ubiquitous expression of the human cDNA with a nucleotide substitution resulting in the amino acid substitution of glutamic acid for alanine at position 93 (A232E). Five lines were created with line 93 selected as the representative line. (J:158713)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:158713
Custer SK et al.,
"Transgenic mice expressing mutant forms VCP/p97 recapitulate the full spectrum of IBMPFD including degeneration in muscle, brain and bone."
Hum Mol Genet 2010 May 1;19(9):1741-55
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All: |
1 reference(s)
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Analysis Tools
