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| Nomenclature |
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Symbol:
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Tg(CAG-VCP*R155H)55Jpat
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Name:
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transgene insertion 55, J Paul Taylor
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MGI ID: |
MGI:4440439 |
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Synonyms: |
VCP-R155H |
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Transgene:
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Tg(CAG-VCP*R155H)55Jpat
Location:
unknown
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The CAG promoter was used to drive ubiquitous expression of the human cDNA with nucleotide substitutions resulting in the amino acid substitution of histidine for arginine at position 155 (R155H). Five lines were created with line 55 selected as the representative line. (J:158713)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:158713
Custer SK et al.,
"Transgenic mice expressing mutant forms VCP/p97 recapitulate the full spectrum of IBMPFD including degeneration in muscle, brain and bone."
Hum Mol Genet 2010 May 1;19(9):1741-55
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All: |
1 reference(s)
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Analysis Tools
