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| Nomenclature |
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Symbol:
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Cd84tm1Pls
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Name:
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CD84 antigen;
targeted mutation 1, Pamela L Schwartzberg
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MGI ID: |
MGI:4438772 |
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Gene:
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Cd84
Location:
Chr1:171839697-171890718 bp, + strand
Genetic Position: Chr1,
79.54 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:157915
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Parent Cell Line:
| Other (see notes) (ES Cell) |
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Strain of Origin:
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C57BL/6J
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The second exon was replaced by two stops codons and a neo cassette by homologous recombination. Lack of expression was verified by flow cytometry. (J:157915)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Cd84 Mutation:
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12 strains or lines available |
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Notes |
ES cell line = HGTC-8.
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| References |
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Original: |
J:157915
Cannons JL et al.,
"Optimal germinal center responses require a multistage T cell:B cell adhesion process involving integrins, SLAM-associated protein, and CD84."
Immunity 2010 Feb 26;32(2):253-65
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All: |
2 reference(s)
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Analysis Tools
