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| Nomenclature |
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Symbol:
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Tg(Thy1-TARDBP)6Singh
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Name:
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transgene insertion 6, Samir Kumar-Singh
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MGI ID: |
MGI:4438491 |
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Synonyms: |
TAR6 |
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Transgene:
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Tg(Thy1-TARDBP)6Singh
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C57BL/6 and SJL
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The cDNA of human TARDBP was driven by Thy1 promoter. Quantitative RT-PCR on brain tissue of 3 week old homozygous mice determined this line to have a 1.2 fold increase over endogenous gene expression. (J:157550)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:157550
Wils H et al.,
"TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration."
Proc Natl Acad Sci U S A 2010 Feb 23;107(8):3858-63
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All: |
1 reference(s)
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Analysis Tools
