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| Nomenclature |
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Symbol:
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Tg(Pkd1)26Mtru
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Name:
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transgene insertion 26, Marie Trudel
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MGI ID: |
MGI:4437718 |
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Synonyms: |
Pkd1TAG |
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Transgene:
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Tg(Pkd1)26Mtru
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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Not Specified
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: A BAC was modifed to insert a silent mutation in exon 10 to act as a tag (G -> A). A second modification removed 34.5 kb of the Tsc2 gene from the BAC. Three lines were created (lines 6, 18, and 26) with 2 to 15 copies of the transgene (2, 6, and 15, respectively). (J:157952)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:157952
Kurbegovic A et al.,
"Pkd1 transgenic mice: adult model of polycystic kidney disease with extrarenal and renal phenotypes."
Hum Mol Genet 2010 Apr 1;19(7):1174-89
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All: |
1 reference(s)
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Analysis Tools
