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| Nomenclature |
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Symbol:
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Mirc30tm1.2Rdf
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Name:
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microRNA cluster 30, including Mir16-1 through Mir15;
targeted mutation 1.2, Riccardo Dalla-Favera
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MGI ID: |
MGI:4437041 |
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Gene:
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Mirc30
Location:
Chr14:61631880-61632110 bp
Genetic Position: Chr14,
Syntenic
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:156946
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Parent Cell Line:
| W9.5/W95 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Deletion, Insertion |
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Mutation details: The locus was floxed and an FRT flanked neo cassette was inserted centromeric to the locus by homologous recombination. The selection cassette was removed by flp mediated recombination and the locus removed by cre mediated recombination. (J:156946)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Mirc30 Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:156946
Klein U et al.,
"The DLEU2/miR-15a/16-1 Cluster Controls B Cell Proliferation and Its Deletion Leads to Chronic Lymphocytic Leukemia."
Cancer Cell 2010 Jan 19;17(1):28-40
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All: |
4 reference(s)
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Analysis Tools
