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| Nomenclature |
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Symbol:
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Del(14Trim13-Dleu2)4Rdf
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Name:
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deletion, Chr 14, Riccardo Dalla-Favera 4
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MGI ID: |
MGI:4437040 |
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Synonyms: |
MDR- |
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Gene:
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Del(14Trim13-Dleu2)4Rdf
Location:
unknown
Genetic Position: Chr14,
Syntenic
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:156946
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Parent Cell Line:
| W9.5/W95 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intergenic deletion |
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Mutation details: The frt-flanked region between
Is(14)1Rdf
and
Is(14)2Rdf
and the GFP reporter were removed by Flp mediated recombination. Portions of Trim13, Kcnrg, Mir15a, Mir16-1, and Dleu2 are deleted.
(J:156946)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Del(14Trim13-Dleu2)4Rdf Mutation:
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0 strains or lines available |
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| References |
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Original: |
J:156946
Klein U et al.,
"The DLEU2/miR-15a/16-1 Cluster Controls B Cell Proliferation and Its Deletion Leads to Chronic Lymphocytic Leukemia."
Cancer Cell 2010 Jan 19;17(1):28-40
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All: |
3 reference(s)
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Analysis Tools
