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| Nomenclature |
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Symbol:
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Tg(Htt-ATXN3*148Q)3746Thsc
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Name:
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transgene insertion 3746, Thorsten Schmidt
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MGI ID: |
MGI:4429385 |
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Synonyms: |
HDPromMJD148 |
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Transgene:
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Tg(Htt-ATXN3*148Q)3746Thsc
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C57BL/6N
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The rat promoter drives whole brain expression of the human cDNA for isoform C. The polyglutamine trinucleotide CAG repeat was expanded to 148 copies (148Q). One line, 3746, was created. (J:156912)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:156912
Boy J et al.,
"A transgenic mouse model of spinocerebellar ataxia type 3 resembling late disease onset and gender-specific instability of CAG repeats."
Neurobiol Dis 2010 Feb;37(2):284-293
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All: |
1 reference(s)
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Analysis Tools
