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| Nomenclature |
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Symbol:
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G6pctm2.2Jyc
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Name:
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glucose-6-phosphatase, catalytic;
targeted mutation 2.2, Janice Yang Chou
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MGI ID: |
MGI:4418685 |
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Synonyms: |
G6pcdelta |
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Gene:
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G6pc
Location:
Chr11:101367561-101377903 bp, + strand
Genetic Position: Chr11,
64.83 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:155990
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Parent Cell Line:
| J1 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exon 3 was floxed and a FRT neo cassette was inserted within intron 3 by homologous recombination. The selection cassette was removed by flp-mediated recombination. Exon 3 was removed by cre-mediated recombination. No detectable G6Pase enzymatic activities are seen in the liver and kidney. (J:155990)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any G6pc Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:155990
Peng WT et al.,
"Generation of mice with a conditional allele for G6pc."
Genesis 2009 Sep;47(9):590-4
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All: |
1 reference(s)
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Analysis Tools
