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| Nomenclature |
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Symbol:
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Ehmt1tm1.1Tara
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Name:
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euchromatic histone methyltransferase 1;
targeted mutation 1.1, Alexander Tarakhovsky
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MGI ID: |
MGI:4418563 |
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Synonyms: |
GLPfl |
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Gene:
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Ehmt1
Location:
Chr2:24790769-24919609 bp, - strand
Genetic Position: Chr2,
16.73 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:155739
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Parent Cell Line:
| E14.1 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: Exon 23 was floxed and an FRT-flanked neo cassette was inserted into intron 23 via homologous recombination. The selection cassette was then removed by flp mediated recombination. Cre-mediated recombination results in out-of-frame splicing and nonsense mediated decay of the mutant transcript. (J:155739)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Ehmt1 Mutation:
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37 strains or lines available |
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| References |
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Original: |
J:155739
Schaefer A et al.,
"Control of cognition and adaptive behavior by the GLP/G9a epigenetic suppressor complex."
Neuron 2009 Dec 10;64(5):678-91
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All: |
2 reference(s)
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Analysis Tools
