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| Nomenclature |
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Symbol:
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Phox2btm3Jbr
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Name:
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paired-like homeobox 2b;
targeted mutation 3, Jean-Francois Brunet
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MGI ID: |
MGI:4418265 |
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Synonyms: |
Phox2blox |
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Gene:
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Phox2b
Location:
Chr5:67094397-67099301 bp, - strand
Genetic Position: Chr5,
35.95 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:155885
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Parent Cell Line:
| CK35 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A loxP site was inserted upstream of exon 2 and an frt flanked neo cassette with a 5' loxP site was inserted upstream of exon 2. (J:155885)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Phox2b Mutation:
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5 strains or lines available |
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| References |
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Original: |
J:155885
Dubreuil V et al.,
"Defective respiratory rhythmogenesis and loss of central chemosensitivity in Phox2b mutants targeting retrotrapezoid nucleus neurons."
J Neurosci 2009 Nov 25;29(47):14836-46
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All: |
4 reference(s)
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Analysis Tools
