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| Nomenclature |
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Symbol:
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Sdhdtm1Jpb
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Name:
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succinate dehydrogenase complex, subunit D, integral membrane protein;
targeted mutation 1, Jean-Pierre Bayley
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MGI ID: |
MGI:4418212 |
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Gene:
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Sdhd
Location:
Chr9:50596340-50603849 bp, - strand
Genetic Position: Chr9,
27.75 cM, cytoband B
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:155380
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: An IRES-LacZ Neo cassette replaced exon 3 by homologous recombination. Quantitative RT-PCR analysis indicated a 50% reduction in expression in multiple tissues from heterozygous mice. (J:155380)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Sdhd Mutation:
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8 strains or lines available |
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| References |
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Original: |
J:155380
Bayley JP et al.,
"Sdhd and SDHD/H19 knockout mice do not develop paraganglioma or pheochromocytoma."
PLoS One 2009;4(11):e7987
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All: |
1 reference(s)
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Analysis Tools
