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| Nomenclature |
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Symbol:
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Atp2a2tm1.1Iemr
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Name:
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ATPase, Ca++ transporting, cardiac muscle, slow twitch 2;
targeted mutation 1.1, Ole Sejersted
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MGI ID: |
MGI:4415164 |
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Synonyms: |
Atp2a2tm1.1Kba, Sercaflox |
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Gene:
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Atp2a2
Location:
Chr5:122453513-122502225 bp, - strand
Genetic Position: Chr5,
62.38 cM, cytoband F
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:155628
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Parent Cell Line:
| E14.1a (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A loxP site was inserted upstream of exon 2 and a floxed neo cassette was inserted downstream of exon 3. Cre mediated recombination removes the neo cassette leaving exons 2 and 3 floxed. (J:155628)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Atp2a2 Mutation:
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30 strains or lines available |
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| References |
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Original: |
J:155628
Andersson KB et al.,
"Mice carrying a conditional Serca2(flox) allele for the generation of Ca(2+) handling-deficient mouse models."
Cell Calcium 2009 Sep;46(3):219-25
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All: |
11 reference(s)
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Analysis Tools
