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| Nomenclature |
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Symbol:
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Clcn7tm3.1Tjj
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Name:
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chloride channel 7;
targeted mutation 3.1, Thomas J Jentsch
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MGI ID: |
MGI:4413670 |
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Synonyms: |
Clcn7lox |
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Gene:
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Clcn7
Location:
Chr17:25133391-25162104 bp, + strand
Genetic Position: Chr17,
12.53 cM, cytoband A3.3
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:155176
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A loxP site was upstream of exon 12 and a floxed neo cassette was inserted downstream of exon 13. Cre mediated recombination removed the neo cassette leaving exons 12 and 13 floxed. (J:155176)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Clcn7 Mutation:
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5 strains or lines available |
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| References |
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Original: |
J:155176
Wartosch L et al.,
"Lysosomal degradation of endocytosed proteins depends on the chloride transport protein ClC-7."
FASEB J 2009 Dec;23(12):4056-68
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All: |
1 reference(s)
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Analysis Tools
