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| Nomenclature |
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Symbol:
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Gt(ROSA)26Sortm7(CAG-mCherry,-EGFP/tetX)Dym
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Name:
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gene trap ROSA 26, Philippe Soriano;
targeted mutation 7, Susan Dymecki
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MGI ID: |
MGI:4412286 |
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Synonyms: |
RC::PFtox |
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Gene:
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Gt(ROSA)26Sor
Location:
Chr6:113067428-113077333 bp, - strand
Genetic Position: Chr6,
52.73 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:154944
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Parent Cell Line:
| TC1/TC-1 (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A CAG promoter drives expression of an EGFP/tetanus toxin light chain (tetX) fusion preceded by a floxed STOP signal and an frt flanked mCherry and STOP signal. Cre mediated removal of the first STOP signal is required for expression of mCherry. Cre and Frt mediated recombination are required to remove both STOP signals to allow for expression of the EGFP/tetX fusion. (J:154944)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Gt(ROSA)26Sor Mutation:
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196 strains or lines available |
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| References |
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Original: |
J:154944
Kim JC et al.,
"Linking genetically defined neurons to behavior through a broadly applicable silencing allele."
Neuron 2009 Aug 13;63(3):305-15
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All: |
2 reference(s)
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Analysis Tools
