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| Nomenclature |
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Symbol:
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Acvrl1tm2Spo
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Name:
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activin A receptor, type II-like 1;
targeted mutation 2, S Paul Oh
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MGI ID: |
MGI:4398904 |
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Synonyms: |
Alk13loxP |
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Gene:
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Acvrl1
Location:
Chr15:101128522-101145336 bp, + strand
Genetic Position: Chr15,
56.41 cM, cytoband F3
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:130020
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A loxP site was inserted upstream of exon 4 and a floxed neo cassette was inserted downstream of exon 6. (J:130020)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Acvrl1 Mutation:
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1 strain or line available |
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| References |
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Original: |
J:130020
Park SO et al.,
"ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2."
Blood 2008 Jan 15;111(2):633-42
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All: |
1 reference(s)
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Analysis Tools
