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| Nomenclature |
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Symbol:
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Sh3tc2tm1.1Rchr
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Name:
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SH3 domain and tetratricopeptide repeats 2;
targeted mutation 1.1, Roman Chrast
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MGI ID: |
MGI:4367025 |
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Synonyms: |
Sh3tc2deltaEx1 |
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Gene:
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Sh3tc2
Location:
Chr18:61953075-62015715 bp, + strand
Genetic Position: Chr18,
34.78 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:153705
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exon 1 was replaced with EGFP and a floxed neo cassette. Germ line, cre mediated recombination removes the neo cassette. (J:153705)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Sh3tc2 Mutation:
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4 strains or lines available |
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| References |
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Original: |
J:153705
Arnaud E et al.,
"SH3TC2/KIAA1985 protein is required for proper myelination and the integrity of the node of Ranvier in the peripheral nervous system."
Proc Natl Acad Sci U S A 2009 Oct 13;106(41):17528-33
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All: |
1 reference(s)
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Analysis Tools
