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| Nomenclature |
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Symbol:
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Tg(Camk2a-App*,-Apbb1)25Spim
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Name:
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transgene insertion 25, Sanjay W Pimplikar
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MGI ID: |
MGI:4366527 |
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Synonyms: |
FeCgamma.25 |
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Transgene:
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Tg(Camk2a-App*,-Apbb1)25Spim
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C57BL/6
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: This bigenic transgene line contains the intracellular domain of App and rat Apbb1 both driven by the mouse Camk2a promoter to achieve forebrain and hippocampal expression. Four lines were created (only lines 12 and 25 were named) that express both cDNAs. Line 25 was selected as the representative line. (J:102815)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:102815
Ryan KA et al.,
"Activation of GSK-3 and phosphorylation of CRMP2 in transgenic mice expressing APP intracellular domain."
J Cell Biol 2005 Oct 24;171(2):327-35
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All: |
5 reference(s)
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Analysis Tools
