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| Nomenclature |
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Symbol:
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Tg(Col2a1-rtTA,tetO-COMP*)2Jath
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Name:
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transgene insertion 2, Jacqueline Hecht
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MGI ID: |
MGI:4361028 |
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Synonyms: |
MT-COMP, Tg(Col2a1-rtTA,TRE-COMP*)2Jath |
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Transgene:
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Tg(Col2a1-rtTA,tetO-COMP*)2Jath
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C57BL/6
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: Bigenic mice contain a rtTA driven by the mouse Col2a1 promoter and human COMP, with the deletion del469D found in patients with pseudoachondroplasia, driven by the tetO promoter. Three line were generated (no line names given).
(J:152756)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:152756
Posey KL et al.,
"An Inducible Cartilage Oligomeric Matrix Protein Mouse Model Recapitulates Human Pseudoachondroplasia Phenotype."
Am J Pathol 2009 Sep 17;():
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All: |
1 reference(s)
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Analysis Tools
