|
|
| Nomenclature |
|
Symbol:
|
Tg(RBP3-ELOVL4*)3Kzh
|
|
Name:
|
transgene insertion 3, Kang Zhang
|
|
MGI ID: |
MGI:4360793 |
|
Transgene:
|
Tg(RBP3-ELOVL4*)3Kzh
Location:
unknown
|
|
Transgene
origin |
|
Strain of Origin:
|
C57BL/6
|
|
Transgene
description |
|
Transgene
Type: | |
Transgenic (random, expressed) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: The human promoter was used to drive photoreceptor-specific expression of a human cDNA with a deletion of AACTT at position 790 to 794 found in patients with Stargardt-like macular dystrophy. Three lines were created (lines 1, 2, and 3) with 0.6, 3.3, and 5.3 times the level of endogenous gene expression, respectively. (J:97173)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
| References |
|
Original: |
J:97173
Karan G et al.,
"Lipofuscin accumulation, abnormal electrophysiology, and photoreceptor degeneration in mutant ELOVL4 transgenic mice: a model for macular degeneration."
Proc Natl Acad Sci U S A 2005 Mar 15;102(11):4164-9
|
|
All: |
1 reference(s)
|
|
Analysis Tools
