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| Nomenclature |
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Symbol:
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Ccr5tm2Blck
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Name:
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chemokine (C-C motif) receptor 5;
targeted mutation 2, Bruno Luckow
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MGI ID: |
MGI:4360353 |
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Gene:
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Ccr5
Location:
Chr9:124121543-124147699 bp, + strand
Genetic Position: Chr9,
75.05 cM, cytoband F
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:152815
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Parent Cell Line:
| E14.1 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutation: | |
Insertion |
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The coding region was replaced with DsRed2 and a floxed hygro cassette. (J:152815)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Ccr5 Mutation:
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4 strains or lines available |
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Notes |
This allele was originally generated in ES cells containing Ccr2tm1Blck.
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| References |
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Original: |
J:152815
Luckow B et al.,
"Microinjection of Cre recombinase protein into zygotes enables specific deletion of two eukaryotic selection cassettes and enhances the expression of a DsRed2 reporter gene in Ccr2/Ccr5 double-deficient mice."
Genesis 2009 Aug;47(8):545-58
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All: |
1 reference(s)
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