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| Nomenclature |
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Symbol:
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Galnt3tm1Mjec
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Name:
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UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3;
targeted mutation 1, Michael J Econs
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MGI ID: |
MGI:4355571 |
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Gene:
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Galnt3
Location:
Chr2:66082766-66124994 bp, - strand
Genetic Position: Chr2,
38.99 cM, cytoband C3
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:151805
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Parent Cell Line:
| CCE916 (ES Cell) |
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Strain of Origin:
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129S/SvEv
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exons 2 and 3 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on kidney extracts. (J:151805)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Galnt3 Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:151805
Ichikawa S et al.,
"Ablation of the Galnt3 gene leads to low-circulating intact fibroblast growth factor 23 (Fgf23) concentrations and hyperphosphatemia despite increased Fgf23 expression."
Endocrinology 2009 Jun;150(6):2543-50
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All: |
2 reference(s)
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Analysis Tools
