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| Nomenclature |
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Symbol:
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Ets2tm5.1Rgo
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Name:
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E26 avian leukemia oncogene 2, 3' domain;
targeted mutation 5.1, Robert G Oshima
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MGI ID: |
MGI:4353393 |
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Synonyms: |
Ets2fl, Ets2LoxP |
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Gene:
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Ets2
Location:
Chr16:95702075-95721051 bp, + strand
Genetic Position: Chr16,
56.64 cM, cytoband C3-qter
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:151187
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A floxed pgk-neo and HSV-TK cassette was inserted into intron 2 and a single loxP site was inserted into intron 5 via homologous recombination. Cre mediated recombination then removed the selection cassette leaving exons 3, 4 and 5 floxed. (J:151187)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Ets2 Mutation:
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6 strains or lines available |
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| References |
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Original: |
J:151187
Wei G et al.,
"Ets1 and Ets2 are required for endothelial cell survival during embryonic angiogenesis."
Blood 2009 Jul 30;114(5):1123-30
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All: |
3 reference(s)
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Analysis Tools
