|
|
| Nomenclature |
|
Symbol:
|
Themistm1Lov
|
|
Name:
|
thymocyte selection associated;
targeted mutation 1, Paul E Love
|
|
MGI ID: |
MGI:4353254 |
|
Synonyms: |
Themis1- |
|
Gene:
|
Themis
Location:
Chr10:28668360-28883818 bp, + strand
Genetic Position: Chr10,
16.06 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:151075
|
|
Parent Cell Line:
| Not Specified (ES Cell) |
|
Strain of Origin:
|
129
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: A neomycin cassette replaced exon 1 of the locus. Gene inactivation was confirmed by a lack detectable protein product in immunoblot analysis of homozygote thymocyte extracts. (J:151075)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Themis Mutation:
|
3 strains or lines available |
|
| References |
|
Original: |
J:151075
Lesourne R et al.,
"Themis, a T cell-specific protein important for late thymocyte development."
Nat Immunol 2009 Aug;10(8):840-7
|
|
All: |
2 reference(s)
|
|
Analysis Tools
