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| Nomenclature |
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Symbol:
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Pbx1tm3.1Mlc
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Name:
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pre B cell leukemia homeobox 1;
targeted mutation 3.1, Michael L Cleary
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MGI ID: |
MGI:4352849 |
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Synonyms: |
Pbx1f |
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Gene:
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Pbx1
Location:
Chr1:168153527-168432270 bp, - strand
Genetic Position: Chr1,
75.95 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:149799
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A loxP site was inserted upstream of exon 3 and a loxP site and an frt flanked selection cassette were inserted downstream of exon 3 via homologous recombination. The selection cassette was then removed by Flp mediated recombination leaving behind a single frt site. (J:149799)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:149799
Ficara F et al.,
"Pbx1 regulates self-renewal of long-term hematopoietic stem cells by maintaining their quiescence."
Cell Stem Cell 2008 May 8;2(5):484-96
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All: |
3 reference(s)
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Analysis Tools
