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| Nomenclature |
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Symbol:
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Rnf7Gt(XE423)Byg
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Name:
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ring finger protein 7;
gene trap XE423, BayGenomics
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MGI ID: |
MGI:4125996 |
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Gene:
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Rnf7
Location:
Chr9:96470941-96478675 bp, - strand
Genetic Position: Chr9,
50.63 cM, cytoband D2.3
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Mutation origin |
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Mutant Cell Line:
| XE423 (BayGenomics) |
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Germline Transmission:
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Earliest citation of germline transmission:
J:164457
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Parent Cell Line:
| Other (see notes) (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation description |
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Allele
Type: | |
Gene trapped |
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Mutation: | |
Insertion of gene trap vector Vector: pGT1Lxf Vector Type: gene trap |
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Mutation details: The gene trap vector inserted in the second intron disrupting the transcript and producing a truncated fusion protein that lacks the RING domain. Immunoblot analysis confirmed the absence of protein expression in homozygous embryos. (J:178926)
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Sequence Tags: |
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Sequence tag details (1 tag)
| Tag ID | GenBank ID | Method |
Tag Location (trapped strand)* | Select |
* GRCh37.p10
(strand of gene trap mutagenesis) |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
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| References |
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Original: |
J:141210
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI),
"Mouse Gene Trap Data Load from dbGSS"
Database Download 2008;():
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All: |
4 reference(s)
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