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| Nomenclature |
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Symbol:
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Acsbg1tm1Mld
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Name:
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acyl-CoA synthetase bubblegum family member 1;
targeted mutation 1, Maria L Dufau
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MGI ID: |
MGI:3851593 |
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Gene:
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Acsbg1
Location:
Chr9:54604877-54661870 bp, - strand
Genetic Position: Chr9,
29.7 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:150391
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A genomic fragment including exons 1 and 2 was replaced with a neo cassette via homologous recombination. Northern blot analysis confirmed the absence of RNA expression in testis from homozygous mice. Western blot analysis confirmed the absence of protein expression in the testis, ovary, adrenal gland, and brain from homozygous mice. (J:150391)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Acsbg1 Mutation:
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7 strains or lines available |
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| References |
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Original: |
J:150391
Sheng Y et al.,
"Lessons from the gonadotropin-regulated long chain acyl-CoA synthetase (GR-LACS) null mouse model: a role in steroidogenesis, but not result in X-ALD phenotype."
J Steroid Biochem Mol Biol 2009 Mar;114(1-2):44-56
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All: |
1 reference(s)
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Analysis Tools
