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| Nomenclature |
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Symbol:
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Tg(Kera-PITX2*A)BHjal
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Name:
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transgene insertion B, Tord Hjalt
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MGI ID: |
MGI:3851245 |
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Synonyms: |
Ktcn-PITX2 |
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Transgene:
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Tg(Kera-PITX2*A)BHjal
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(CBA x C57BL/6)F2
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: A transgenic construct containing cDNA for the human paired-like homeodomain 2, human, PITX2A, isoform under the control of the mouse keratocan ( Kera) promoter, and rabbit beta-globin polyA signal sequences was injected into fertilized CBAB6F2 mouse eggs. Numerous founders were obtained. In line B, multiple copies were found to be integrated on chromosome 12B3. Lines A and B display identical phenotypes.
(J:93634)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:93634
Holmberg J et al.,
"PITX2 gain-of-function in rieger syndrome eye model."
Am J Pathol 2004 Nov;165(5):1633-41
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All: |
2 reference(s)
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Analysis Tools
