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| Nomenclature |
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Symbol:
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Clrn1tm1.1Kuna
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Name:
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clarin 1;
targeted mutation 1.1, Kumar N Alagramam
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MGI ID: |
MGI:3850171 |
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Gene:
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Clrn1
Location:
Chr3:58844028-58885340 bp, - strand
Genetic Position: Chr3,
28.78 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:150215
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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C57BL/6J
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Germ line, cre mediated recombination removes the neo cassette and exon 1. RT-PCR on P30 and P60 cochlear extracts confirmed the absence of transcript expression. (J:150215)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Clrn1 Mutation:
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1 strain or line available |
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| References |
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Original: |
J:150215
Geng R et al.,
"Usher syndrome IIIA gene clarin-1 is essential for hair cell function and associated neural activation."
Hum Mol Genet 2009 Aug 1;18(15):2748-60
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All: |
5 reference(s)
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Analysis Tools
