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| Nomenclature |
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Symbol:
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Smad9tm3Jfm
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Name:
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SMAD family member 9;
targeted mutation 3, James F Martin
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MGI ID: |
MGI:3850120 |
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Synonyms: |
Smad8lacZ |
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Gene:
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Smad9
Location:
Chr3:54755582-54801257 bp, + strand
Genetic Position: Chr3,
25.62 cM, cytoband D
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:150213
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Parent Cell Line:
| AK7 (ES Cell) |
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Strain of Origin:
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129S4/SvJaeSor
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: An IRES-lacZ and floxed pgk-neo cassette was inserted into exon 4 via homologous recombination. Immunostaining analysis confirmed the absence of endogenous protein and presence of LacZ expression in prostates from homozygous mice. (J:150213)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Smad9 Mutation:
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6 strains or lines available |
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| References |
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Original: |
J:150213
Huang Z et al.,
"Defective pulmonary vascular remodeling in Smad8 mutant mice."
Hum Mol Genet 2009 Aug 1;18(15):2791-801
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All: |
1 reference(s)
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Analysis Tools
