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| Nomenclature |
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Symbol:
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Tg(Kera-cre)KC4.3Wwk
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Name:
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transgene insertion KC4.3, Winston W Y Kao
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MGI ID: |
MGI:3849605 |
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Synonyms: |
KC4.3, Kera-Cre |
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Transgene:
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Tg(Kera-cre)KC4.3Wwk
Location:
unknown
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: A minigene containing a 3.2 kb fragment 5' of the transcription start site of the Kera gene, exon 1 (172 bp), intron 1 (1.4 kb), exon 2 (7 bp) preceding the ATG start codon of the Kera mRNA, and a cre minigene with IRES and nuclear localization sequences (NLS) followed by the SV40 polyadenylation (pA) signal, was injected into FVB/N oocytes. Mice were crossed with R26R reporter mice to assess cre activity. Founder line KC4.3, showing strong expression and line KC4.1 with moderate expression were characterized further. (J:149921)
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:149921
Weng DY et al.,
"Promiscuous recombination of LoxP alleles during gametogenesis in cornea Cre driver mice."
Mol Vis 2008;14():562-71
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All: |
2 reference(s)
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Analysis Tools
