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| Nomenclature |
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Symbol:
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Mycbp2m274-4Tpo
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Name:
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MYC binding protein 2;
mutation 274-4, Timothy P O'Brien
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MGI ID: |
MGI:3849603 |
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Synonyms: |
Phr274-4 |
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Gene:
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Mycbp2
Location:
Chr14:103113411-103346814 bp, - strand
Genetic Position: Chr14,
51.79 cM
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Mutation
origin |
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Strain of Origin:
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SSL/LeJ
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Single point mutation |
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Mutation details: ENU mutagenesis induced a T to A transversion at position 2599 in exon 15. This point mutation results in termination of protein translation instead of coding for a cystein at position 772 (C772X). The protein product is truncated after the second RCC1 homology domain. (J:149893)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Mycbp2 Mutation:
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6 strains or lines available |
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Notes |
Strain of origin for this mutation was determined by its close linkage to Ednrbs (J:149893).
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| References |
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Original: |
J:149893
Hagarman JA et al.,
"An essential gene mutagenesis screen across the highly conserved piebald deletion region of mouse chromosome 14."
Genesis 2009 Jun;47(6):392-403
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All: |
1 reference(s)
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Analysis Tools
