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| Nomenclature |
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Symbol:
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Tg(CAG-RAB9A)500Repa
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Name:
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transgene insertion 500, Richard E Pagano
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MGI ID: |
MGI:3849445 |
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Synonyms: |
Rab9TG, Rab9TG |
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Transgene:
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Tg(CAG-RAB9A)500Repa
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x CBA)F1 X C57BL/6
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: A transgenic construct containing a HA-tagged human RAB9A, member RAS oncogene family, gene (RAB9A) under the control of the CAG promoter (CAGGS, chicken beta actin promoter/enhancer coupled with the cytomegalovirus immediate-early enhancer), was injected into fertilized (C57BL/6 X CBA)F1 X C57BL/6 mouse eggs. Founder line 500 was subsequently established. Expression is approximately 30-fold higher than endogenous Rab9 protein in the liver. (J:144240)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:144240
Kaptzan T et al.,
"Development of a Rab9 transgenic mouse and its ability to increase the lifespan of a murine model of Niemann-Pick type C disease."
Am J Pathol 2009 Jan;174(1):14-20
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All: |
1 reference(s)
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Analysis Tools
