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| Nomenclature |
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Symbol:
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Six1Cwe
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Name:
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sine oculis-related homeobox 1;
Catweasel
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MGI ID: |
MGI:3849082 |
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Synonyms: |
ABE4 |
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Gene:
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Six1
Location:
Chr12:73041827-73046712 bp, - strand
Genetic Position: Chr12,
30.34 cM
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Mutation
origin |
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Strain of Origin:
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C3HeB/FeJ
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Single point mutation |
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Mutation details: ENU mutagenesis induced an A to G transition at position 411 resulting in an amino acid substitution of glycine for glutamic acid at position 135 (E135G). This mutation in the homeobox is predicted to cause destabilisation of DNA binding. (J:149467)
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Inheritance: | |
Dominant |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:149467
Bosman EA et al.,
"Catweasel mice: a novel role for Six1 in sensory patch development and a model for branchio-oto-renal syndrome."
Dev Biol 2009 Apr 15;328(2):285-96
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All: |
2 reference(s)
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Analysis Tools
