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| Nomenclature |
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Symbol:
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Cdkn2atm1Sxs
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Name:
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cyclin-dependent kinase inhibitor 2A;
targeted mutation 1, Stephen X Skapek
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MGI ID: |
MGI:3848992 |
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Synonyms: |
ArflacZ |
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Gene:
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Cdkn2a
Location:
Chr4:89274473-89294653 bp, - strand
Genetic Position: Chr4,
42.15 cM, cytoband C3-C6
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:149526
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129/Sv
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exon1b was replaced with a cassette containing lacZ and neo in opposite orientations. LacZ expression recapitulates endogenous gene expression in the eye and testis. (J:149526)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Cdkn2a Mutation:
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22 strains or lines available |
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| References |
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Original: |
J:149526
Freeman-Anderson NE et al.,
"Expression of the Arf tumor suppressor gene is controlled by Tgf{beta}2 during development."
Development 2009 Jun;136(12):2081-9
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All: |
2 reference(s)
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Analysis Tools
