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| Nomenclature |
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Symbol:
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Plxnd1tm1.1Tmj
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Name:
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plexin D1;
targeted mutation 1.1, Thomas M Jessell
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MGI ID: |
MGI:3848812 |
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Synonyms: |
plexinD1flox |
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Gene:
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Plxnd1
Location:
Chr6:115954811-115995005 bp, - strand
Genetic Position: Chr6,
53.72 cM
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Increase in extraretinal vascular outgrowth in ischemic Plxnd1tm1.1Tmj/Plxnd1tm1Ddg Tg(CAG-cre/Esr1*)1Egwa/0 retinas
Show the 2 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:143763
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129S/SvEv
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: An frt flanked neo cassette with a loxP site was inserted upstream of exon 1 and an additional loxP site was inserted downstream of exon 1. Germ line, flp mediated recombination removed the neo cassette leaving exon 1 floxed. (J:143763)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:143763
Zhang Y et al.,
"Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects."
Dev Biol 2009 Jan 1;325(1):82-93
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All: |
7 reference(s)
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Analysis Tools
