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| Nomenclature |
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Symbol:
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Nagstm1(KOMP)Vlcg
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Name:
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N-acetylglutamate synthase;
targeted mutation 1, Velocigene
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MGI ID: |
MGI:3847452 |
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Gene:
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Nags
Location:
Chr11:102145513-102149477 bp, + strand
Genetic Position: Chr11,
65.48 cM
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Mutation
origin |
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Mutant Cell Lines:
| 10229B-H2, 10229E-B5 (Velocigene) |
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Germline Transmission:
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Earliest citation of germline transmission:
J:184448
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Parent Cell Line:
| VGB6 (ES Cell) |
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Strain of Origin:
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C57BL/6NTac
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion Vector: ZEN-Ub1 |
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Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 3502bp between positions 102006884-102010385 of Chromosome 11 (Genome Build37). Western blot analysis confirmed the absence of protein expression in the liver and intestines of homozygous mice. (J:136110, J:184448)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:136110
Velocigene,
"Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)"
MGI Direct Data Submission 2008;():
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All: |
2 reference(s)
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Analysis Tools
