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| Nomenclature |
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Symbol:
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Tg(SMN2*)1951Ahmb
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Name:
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transgene insertion 1951, Arthur H M Burghes
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MGI ID: |
MGI:3847329 |
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Synonyms: |
line 1951, SMN(VDQNQKE) |
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Transgene:
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Tg(SMN2*)1951Ahmb
Location:
unknown
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The transgenic construct encodes a truncated form of SMN2 (exons 1-6) with the added motif VDQNQKE under control of a 4.1 kb SMN2 promoter. Ten founder lines were obtained and lines 1946, 1947, and 1951 (which received more characterization) were established. (J:148541)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:148541
Workman E et al.,
"A SMN missense mutation complements SMN2 restoring snRNPs and rescuing SMA mice."
Hum Mol Genet 2009 Jun 15;18(12):2215-29
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All: |
1 reference(s)
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Analysis Tools
