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| Nomenclature |
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Symbol:
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Tg(SMN2*A111G)588Ahmb
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Name:
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transgene insertion 588, Arthur H M Burghes
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MGI ID: |
MGI:3847324 |
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Synonyms: |
A588, A591, line 588, line 591, SMN(A111G) |
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Transgene:
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Tg(SMN2*A111G)588Ahmb
Location:
unknown
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: A transgenic construct containing the SMN(A111G) missense mutation under the control of 4.1 kb SMN promoter was injected into fertilized FVB/N mouse eggs. Eleven founder lines were obtained and line 588 was subsequently established. This line was found to have 4 copies of the transgene. (J:148541)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:148541
Workman E et al.,
"A SMN missense mutation complements SMN2 restoring snRNPs and rescuing SMA mice."
Hum Mol Genet 2009 Jun 15;18(12):2215-29
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All: |
1 reference(s)
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Analysis Tools
