|
|
| Nomenclature |
|
Symbol:
|
Tg(CAG-PKD2)#Hwl
|
|
Name:
|
transgene insertion, Han-Woong Lee
|
|
MGI ID: |
MGI:3844550 |
|
Transgene:
|
Tg(CAG-PKD2)#Hwl
Location:
unknown
|
|
Transgene
origin |
|
Transgene
description |
|
Transgene
Type: | |
Transgenic (random, expressed) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: The chicken beta actin promoter and cytomegalovirus immediate early enhancer (pCAGGS) drive expression of a human PKD2 cDNA. Four lines (C, D, E, F) were generated all containing multiple copies of the transgene. Semi quantitative RT-PCR and western blot analysis confirmed expression of the transgene in the kidneys. This record is for data pooled from multiple lines. (J:148377)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
| References |
|
Original: |
J:148377
Park EY et al.,
"Cyst formation in kidney via B-Raf signaling in the PKD2 transgenic mice."
J Biol Chem 2009 Mar 13;284(11):7214-22
|
|
All: |
1 reference(s)
|
|
Analysis Tools
