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| Nomenclature |
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Symbol:
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Ank1RBC2
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Name:
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ankyrin 1, erythroid;
red blood cell mutant 2
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MGI ID: |
MGI:3844284 |
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Synonyms: |
Ank-11674 |
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Gene:
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Ank1
Location:
Chr8:22974844-23150497 bp, + strand
Genetic Position: Chr8,
11.42 cM
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Mutation
origin |
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Strain of Origin:
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129S1/Sv and BALB/c
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Single point mutation |
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Mutation details: ENU treatment of male mice with Mpltm1Wsa on a BALB/c background induced a G to C transversion located at the splice acceptor site of exon 41. This point mutation induces a frame shift after amino acid 1674 and results in the addition of 96 residues and a premature codon. (J:148127)
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Inheritance: | |
Dominant |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Ank1 Mutation:
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5 strains or lines available |
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| References |
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Original: |
J:148127
Rank G et al.,
"Novel roles for erythroid Ankyrin-1 revealed through an ENU-induced null mouse mutant."
Blood 2009 Apr 2;113(14):3352-62
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All: |
2 reference(s)
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Analysis Tools
